Oral Drug Absorption: Prediction and Assessment (Drugs and by Jennifer B. Dressman,Hans Lennernas

By Jennifer B. Dressman,Hans Lennernas

a pragmatic, hands-on consultant for effectively constructing oral drug items, this accomplished reference runs the gamut from theoretical phases of computer-based calculations to functional directions for developing in vitro/in vivo correlations. insurance info the interrelationship among the body structure of the gastrointestinal tract and oral drug formulations and absorption, and progresses to the newest purposes of pharmacokinetic research.
Includes chapters through the innovators of the Biopharmaceutical category Scheme (BCS), human perfusions, and biorelevant dissolution testing!
With over six hundred literature references, equations, drawings, and pictures, Oral Drug Absorption

  • offers a number of equipment for predicting permeability, solubility, and dissolution for oral bioavailability and bioequivalence
  • facilitates number of acceptable drug applicants for improvement
  • fully elaborates at the experimental and knowledge research innovations of in vitro/in vivo correlations
  • provides suggestions to the Federal Drug Administration's BCS and its functions
  • appends necessary case reviews to the strategies mentioned
  • and a lot more!
    Contributions by means of greater than 20 overseas experts at the most recent learn make Oral Drug Absorption a useful instrument and worthy reference within the fingers of pharmaceutical scientists, medicinal chemists, pharmacists, pharmacologists, toxicologists, biochemists, gastroenterologists, regulatory body of workers, and graduate college scholars in those disciplines.
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