Sex Steroids and the Cardiovascular System (Ernst Schering by Peter Ramwell,G. Rubanyi,E. Schillinger

By Peter Ramwell,G. Rubanyi,E. Schillinger

facts collected during the last decade exhibit that gonadal steroid hormones perform a massive approach within the physiological and pop­ thophysiological law of the cardiovascular method. The hor­ monal profile appears to be like to place men at an obstacle biologically when it comes to cardiovascular ailments. The prevalence of high blood pressure is greater in males than in pre-monopausal girls indicating a power of gender at the hypertensive sickness method. men and women have identical levels of cholesterol till puberty yet men endure an ex­ ponential elevate in middle disorder of their forties, whereas the feminine upward thrust doesn't begin until eventually a decade later, after menopause. Animal and human reviews supplied considerable facts, that estrogens decrease the degrees of low density lipoproteins and continue excessive density lipoproteins increased. those adjustments might be helpful within the prevention of center diesease. Co­ ronary artery atherosclerosis has been proven to be extra said in ovarectomized girl monkeys as in intact ladies. Androgen, con­ versely, lowers the excessive density lipoproteins and elevates low density lipoproteins. relating to blood strain, it's good validated that high blood pressure is extra serious or develops extra swiftly in male than fe­ male rats in numerous genetic different types of high blood pressure, and that gonadal steroid hormones are most likely taking part in an immense function in explaining this commentary. possibility components of human high blood pressure and heart dies ease contain menopause and ovarectomy.

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